Anti-Mouse Kdm6a Antibody (C-term)
Boster Bio Anti-Mouse Kdm6a Antibody (C-term) (Catalog # M01286) . Tested in WB application (s) . This antibody reacts with Mouse.
Product Specifications
Background
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity) .
Synonyms
Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously transcribed TPR protein on the X chromosome, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein, Kdm6a, Utx
Gene Name
Kdm6a
UniProt
O70546
Host
Rabbit
Reactivity
Mouse
Immunogen
This mouse Kdm6a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1041-1074 amino acids from the C-terminal region of mouse Kdm6a.
Clonality
Polyclonal
Tissue Specificity
Expressed in brain, heart and spleen.
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
21095589
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
154355 Da
Applications Notes
WB: 1:2000
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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