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Anti-STMN1 Antibody (C-Term)

Boster Bio Anti-STMN1 Antibody (C-Term) (Catalog # M01194-2) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Rat.

Product Specifications

Background

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity) .

Synonyms

Stathmin, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17, STMN1, C1orf215, LAP18, OP18

Gene Name

STMN1

UniProt

P16949

Host

Rabbit

Reactivity

Human, Rat

Immunogen

This STMN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 106-140 amino acids from human STMN1.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.

Applications

WB, Flow Cytometry

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01194-2

Product MSDS

https://www.bosterbio.com/msds?sku=M01194-2

Observed Molecular Weight

17303 Da

Subcellular Location

Cytoplasm, cytoskeleton.

Prediction Reactivity

Bovine, Monkey, Pig

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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