Anti-BNP NPPB Monoclonal Antibody (KLH)
Boster Bio Anti-BNP NPPB Monoclonal Antibody (KLH) catalog # M01186. Tested in IHC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Natriuretic peptides B; Gamma-brain natriuretic peptide; Brain natriuretic peptide 32; BNP (1-32) ; BNP-32; BNP (1-30) ; BNP (1-29) ; BNP (1-28) ; BNP (2-31) ; BNP (3-32) ; BNP (3-30) ; BNP (3-29) ; BNP (4-32) ; BNP (4-31) ; BNP (4-30) ; BNP (4-29) ; BNP (4-27) ; BNP (5-32) ; BNP (5-31) ; BNP (5-29) ; NPPB
Gene Name
NPPB
UniProt
P16860
Host
Mouse
Reactivity
Human
Immunogen
Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH.
Clonality
Monoclonal
Clone
Clone: 8D5B4C11
Tissue Specificity
Brain and also in atria, but at much lower levels than ANP.
Applications
IHC, IF, ELISA
Purification
Affinity purification
Concentration
1 mg/mL
Form
Liquid
Function
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
14726 MW
Gene Name Synonym
Natriuretic peptides B
Subcellular Location
Secreted.
Protein Name
Natriuretic peptides B
Isotype
IgG
Contents
Ascitic fluid containing 0.03% sodium azide.
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