Anti-PBRM1 Antibody (C-term)
Boster Bio Anti-PBRM1 Antibody (C-term) (Catalog # M01130-1) . Tested in WB application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Acts as a negative regulator of cell proliferation.
Synonyms
Protein polybromo-1, hPB1, BRG1-associated factor 180, BAF180, Polybromo-1D, PBRM1, BAF180, PB1
Gene Name
PBRM1
UniProt
Q86U86
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PBRM1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1121-1155 amino acids from the C-terminal region of human PBRM1.
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) . Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF) . Acts as a negative regulator of cell proliferation.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
192948 Da
Applications Notes
WB: 1:2000
Subcellular Location
Nucleus
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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