Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MGMT Antibody

Boster Bio Anti-MGMT Antibody (Catalog # M01012-2) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human.

Product Specifications

Background

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Synonyms

Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT

Gene Name

MGMT

UniProt

P16455

Host

Mouse

Reactivity

Human

Immunogen

This MGMT antibody is generated from a mouse immunized with a recombinant protein.

Clonality

Monoclonal

Clone

Clone: 1527CT158.87.44

Applications

WB, Flow Cytometry

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

21646 Da

Subcellular Location

Nucleus.

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Dividers for 32 mm boxes, grid 8 x 8, H: 22 mm
TE22091 36 Cases

Dividers for 32 mm boxes, grid 8 x 8, H: 22 mm

Ask
View Details
Asb2 (NM_001011984) Rat Tagged Lenti ORF Clone
RR204703L4 10 µg

Asb2 (NM_001011984) Rat Tagged Lenti ORF Clone

Ask
View Details
MAPK1IP1L Human shRNA Lentiviral Particle (Locus ID 93487)
TL306175V 500 µL Each

MAPK1IP1L Human shRNA Lentiviral Particle (Locus ID 93487)

Ask
View Details
Human PAS1C1 (LMNTD1) (NM_001145728) AAV Particle
RC226928A1V 250 µL

Human PAS1C1 (LMNTD1) (NM_001145728) AAV Particle

Ask
View Details
Human Immunoglobulin M (IgM) ELISA Kit
JLO10665-01 48 Tests

Human Immunoglobulin M (IgM) ELISA Kit

Ask
View Details
Human Immunoglobulin M (IgM) ELISA Kit
JLO10665-02 96 Tests

Human Immunoglobulin M (IgM) ELISA Kit

Ask
View Details