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Anti-CD34 Antibody (C-term)

Boster Bio Anti-CD34 Antibody (C-term) (Catalog # M00885) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Synonyms

Hematopoietic progenitor cell antigen CD34, CD34, CD34

Gene Name

CD34

UniProt

P28906

Host

Rabbit

Reactivity

Human

Immunogen

This CD34 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 356-390 amino acids from the C-terminal region of human CD34.

Clonality

Polyclonal

Tissue Specificity

Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues

Applications

Flow Cytometry, WB

Field of Research

Cancer, Cardiovascular, Developmental Biology, Immunology, Neuroscience, Signal Transduction, Stem Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

40716 Da

Subcellular Location

Membrane; Single-pass type I membrane protein.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Curated Selection

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