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Anti-DNA repair protein XRCC4 XRCC4 Monoclonal Antibody

Selected Variant

M00787

Size: 100 µL

Boster Bio Anti-DNA repair protein XRCC4 XRCC4 Monoclonal Antibody catalog # M00787. Tested in WB, IHC, IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

DNA repair protein XRCC4; X-ray repair cross-complementing protein 4; XRCC4

Gene Name

XRCC4

UniProt

Q13426

Host

Mouse

Reactivity

Human

Immunogen

Synthetic Peptide of XRCC4

Clonality

Monoclonal

Clone

Clone: 5C10

Tissue Specificity

Widely expressed.

Applications

WB, IHC, IF, IP

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. Binds to DNA and to DNA ligase IV (LIG4) . The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

38287 MW

Gene Name Synonym

DNA repair protein XRCC4

Subcellular Location

Nucleus

Protein Name

DNA repair protein XRCC4

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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