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Anti-PRDM16 Antibody

Boster Bio Anti-PRDM16 Antibody (Catalog # M00782) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Synonyms

PR domain zinc finger protein 16, PR domain-containing protein 16, Transcription factor MEL1, MDS1/EVI1-like gene 1, PRDM16, KIAA1675, MEL1, PFM13

Gene Name

PRDM16

UniProt

Q9HAZ2

Host

Mouse

Reactivity

Human

Immunogen

This PRDM16 antibody is generated from a mouse immunized with a recombinant protein between 779-996 amino acids from PRDM16.

Clonality

Monoclonal

Clone

Clone: 1740CT793.52.44

Tissue Specificity

Expressed in uterus and kidney. Expressed in both cardiomyocytes and interstitial cells.

Applications

WB

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

1281687219049980

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

140251 Da

Applications Notes

WB: 1:4000

Subcellular Location

Nucleus. Cytoplasm

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Curated Selection

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