Anti-PLCG1 Antibody (Center)
Boster Bio Anti-PLCG1 Antibody (Center) (Catalog # M00677-1) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Synonyms
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, PLC-II, Phospholipase C-gamma-1, PLC-gamma-1, PLCG1, PLC1
Gene Name
PLCG1
UniProt
P19174
Host
Rabbit
Reactivity
Human
Immunogen
This PLCG1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 456-488 amino acids from the Central region of human PLCG1.
Clonality
Polyclonal
Applications
WB
Field of Research
Cancer, Cardiovascular, Metabolism, Signal Transduction, Viral process, Host-Virus Interaction, T Cells, Inflammation
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
17229814
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
148532 Da
Applications Notes
WB: 1:2000
Subcellular Location
Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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