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Anti-Hu CD69 Purified Monoclonal Antibody

Boster Bio Anti-Hu CD69 Purified Monoclonal Antibody (Catalog# M00529) . Tested in Flow Cytometry, IHC-F application (s) . This antibody reacts with Human.

Product Specifications

Background

CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.

Synonyms

EA1, AIM, MLR-3, CLEC2C, GP32/28, BL-AC/P26

Gene Name

CD69

UniProt

Q07108

Host

Mouse

Reactivity

Human

Immunogen

Anti-mu-stimulated human B lymphocytes. The mouse monoclonal antibody FN50 recognizes an extracellular epitope of CD69, an lymphocyte early activation marker.

Clonality

Monoclonal

Clone

Clone: FN50

Tissue Specificity

Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

Applications

Flow Cytometry, IHC-F

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

Storage Conditions

Store at 2-8°C. Do not freeze.

Observed Molecular Weight

22559 MW

Applications Notes

Flow cytometry: 1-4 μg/mL.

Gene Name Synonym

CD69 molecule

Subcellular Location

Membrane; Single-pass type II membrane protein.

Protein Name

Early activation antigen CD69

Isotype

Mouse IgG1

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

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