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Anti-CCR7 Antibody (N-term)

Boster Bio Anti-CCR7 Antibody (N-term) (Catalog # M00390-1) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Synonyms

C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, CCR7, CMKBR7, EBI1, EVI1

Gene Name

CCR7

UniProt

P32248

Host

Mouse

Reactivity

Human

Immunogen

This CCR7 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 26-57 amino acids from the N-terminal region of human CCR7.

Clonality

Monoclonal

Clone

Clone: 1987CT875.52.22

Tissue Specificity

Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7

Applications

WB

Field of Research

Immunology, Signal Transduction, Chemokine signaling, Inflammation

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

42874 Da

Applications Notes

WB: 1:4000

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Prediction Reactivity

Human

Isotype

IgG1, κ

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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