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Anti-TPM3 Antibody

Boster Bio Anti-TPM3 Antibody (Catalog # M00381) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Synonyms

Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3

Gene Name

TPM3

UniProt

P06753

Host

Mouse

Reactivity

Human, Mouse

Immunogen

This TPM3 antibody is generated from a mouse immunized with a recombinant protein of human TPM3.

Clonality

Monoclonal

Clone

Clone: 1649CT306.29.13

Applications

WB

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

32950 Da

Applications Notes

WB: 1:2000

Subcellular Location

Cytoplasm, cytoskeleton.

Isotype

IgG1, k

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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