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Anti-Thyroglobulin TG Monoclonal Antibody

Boster Bio Anti-Thyroglobulin TG Monoclonal Antibody (Catalog # M00359) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat, Dog.

Product Specifications

Background

Thyroglobulin (Tg) is synthesized by the follicular epithelial cells of the thyroid and secreted from the thyroid gland with the stimulation of TSH and/or thyroid stimulating immunoglobulins. Thyroglobulin is a prognostic marker for Graves` disease. Thyroglobulin antibody has been useful in the positive identification of thyroid carcinomas of the papillary and follicular types.

Synonyms

Thyroglobulin, AITD 3, AITD3, hTG, TDH3, Tg, TGN

Gene Name

TG

UniProt

P01266

Host

Mouse

Reactivity

Canine, Human, Mouse, Rat

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

This protein A purified monoclonal antibody was produced by repeated immunizations with human thyroglobulin protein.

Clonality

Monoclonal

Clone

Clone: Clone: 2H11

Tissue Specificity

Thyroid gland specific.

Applications

ELISA, IHC, WB

Purification

This protein A purified mouse monoclonal antibody reacts specifically with thyroglobulin in human tissues. The antibody recognizes a 330-kDa band corresponding to thyroglobulin. Cross-reactivity with thyroglobulin from mouse, rat and dog will occur. Cross-reactivity with thyroglobulin from other sources has not been determined.

Concentration

1.6 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Function

Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) .

Shipping Conditions

Dry Ice Shipping

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Observed Molecular Weight

304790 MW

Gene Name Synonym

Thyroglobulin

Subcellular Location

Secreted.

Prediction Reactivity

Canine

Isotype

IgG1

Contents

0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

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