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Anti-BMI1 Antibody (C-term)

Boster Bio Anti-BMI1 Antibody (C-term) (Catalog # M00313-1) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Synonyms

Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51

Gene Name

BMI1

UniProt

P35226

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This BMI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 281-314 amino acids from the C-terminal region of human BMI1.

Clonality

Polyclonal

Applications

WB, IF

Field of Research

Cancer, Cell Biology, Stem Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

153860221635990126151332167142942177224925355358278273732177224925355358153860222615133221772249

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

36949 Da

Subcellular Location

Nucleus. Cytoplasm

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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