Anti- (Mouse) Epcam Antibody (C-term)
Boster Bio Anti- (Mouse) Epcam Antibody (C-term) (Catalog # M00276-1) . Tested in WB, IHC-P application (s) . This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity) .
Synonyms
Epithelial cell adhesion molecule, Ep-CAM, Epithelial glycoprotein 314, EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, Epcam, Tacstd1
Gene Name
Epcam
UniProt
Q99JW5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This Mouse Epcam antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 217-251 amino acids from the C-terminal region of Mouse Epcam.
Clonality
Polyclonal
Applications
WB, IHC-P
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
35019 Da
Subcellular Location
Lateral cell membrane {ECO:0000250|UniProtKB:P16422}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P16422}. Cell junction, tight junction {ECO:0000250|UniProtKB:P16422}. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction {ECO:0000250|UniProtKB:P16422}
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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