Anti-SOCS3 Purified Monoclonal Antibody
Boster Bio Anti-SOCS3 Purified Monoclonal Antibody (Catalog# M00274) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.
Synonyms
SOCS-3, CIS3, SSI3
Gene Name
SOCS3
UniProt
Q6FI39
Host
Mouse
Reactivity
Human
Immunogen
Full-length SOCS3 protein. The antibody SO1 reacts with SOCS3, an intracellular cytokine signaling inhibitor.
Clonality
Monoclonal
Clone
Clone: SO1
Applications
WB
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/mL
Form
Liquid
Storage Conditions
Store at 2-8°C. Do not freeze.
Applications Notes
Western blotting: Positive control: HeLa human cervix carcinoma cell line, reducing conditions.
Gene Name Synonym
Suppressor of cytokine signaling 3
Isotype
Mouse IgG2b
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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