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Anti-VWF Antibody

Boster Bio Anti-VWF Antibody (Catalog # M00270-2) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Synonyms

Von Willebrand factor, vWF, von Willebrand antigen 2, von Willebrand antigen II, VWF, F8VWF

Gene Name

VWF

UniProt

P04275

Host

Mouse

Reactivity

Human

Immunogen

This antibody is generated from a mouse immunized with .VWF recombinant protein.

Clonality

Monoclonal

Clone

Clone: 907CT12.1.9

Tissue Specificity

Plasma.

Applications

WB, Flow Cytometry, IHC-P

Field of Research

Cancer, Cardiovascular, Signal Transduction, Inflammation

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

309265 Da

Subcellular Location

Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules

Isotype

IgG1

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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