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Anti-Mouse Klf4 Antibody (Center)

Boster Bio Anti-Mouse Klf4 Antibody (Center) (Catalog # M00120-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Mouse.

Product Specifications

Background

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity) .

Synonyms

Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, Klf4, Ezf, Gklf, Zie

Gene Name

Klf4

UniProt

Q60793

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Klf4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the Central region of mouse Klf4.

Clonality

Polyclonal

Tissue Specificity

Highest expression in the colon. Lower levels in testis, lung and small intestine

Applications

WB, Flow Cytometry

Field of Research

Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

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Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

51880 Da

Subcellular Location

Nucleus. Cytoplasm

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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