Anti-Transferrin Antibody
Boster Bio Anti-Transferrin Antibody (Catalog # M00094-3) . Tested in WB, IF application (s) . This antibody reacts with Human.
Product Specifications
Background
Transferrins are iron binding transport proteins which can bind two Fe (3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Synonyms
Serotransferrin, Transferrin, Beta-1 metal-binding globulin, Siderophilin, TF
Gene Name
TF
UniProt
P02787
Host
Rabbit
Reactivity
Human
Immunogen
This Transferrin antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 101-135 amino acids from human Transferrin.
Clonality
Polyclonal
Tissue Specificity
Expressed by the liver and secreted in plasma.
Applications
WB, IF
Field of Research
Cardiovascular, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transferrins are iron binding transport proteins which can bind two Fe (3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
77050 Da
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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