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Anti-BRAF V600E Antibody (C-Term)

Boster Bio Anti-BRAF V600E Antibody (C-Term) (Catalog # M00075-4) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

Synonyms

Serine/threonine-protein kinase B-raf, 2.7.11.1, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1

Gene Name

BRAF

UniProt

P15056

Host

Rabbit

Reactivity

Human

Immunogen

This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 576-606 amino acids from human.

Clonality

Polyclonal

Tissue Specificity

Brain and testis.

Applications

WB, IHC-P

Field of Research

Cancer, Cell Biology, Signal Transduction, T Cells, Chemokine signaling, Inflammation, Interleukins

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

2144191029433126364027891508179

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

84437 Da

Subcellular Location

Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.

Prediction Reactivity

Mouse, Rat, Chicken, Bovine

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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