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Anti-F2 Antibody (N-Term)

Boster Bio Anti-F2 Antibody (N-Term) (Catalog # M00044-1) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

Synonyms

Prothrombin, Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain, F2

Gene Name

F2

UniProt

P00734

Host

Rabbit

Reactivity

Human

Immunogen

This F2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 46-79 amino acids from human F2.

Clonality

Polyclonal

Tissue Specificity

Expressed by the liver and secreted in plasma.

Applications

WB

Field of Research

Cardiovascular, Cell Biology, Metabolism, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

70037 Da

Applications Notes

WB: 1:2000

Subcellular Location

Secreted, extracellular space.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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