IND 1316
IND 1316 is an orally active, blood-brain barrier permeable AMPK activator with neuroprotective effects in animal models of Huntington's disease. IND 1316 can be used for research on neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease[1].
Product Specifications
CAS Number
1888473-12-8
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ind-1316.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C2=CC(OCC3=CC=CC=C3)=CC=C2)C4=C(C=CC=C4)N1)O
Molecular Formula
C22H17NO3
Molecular Weight
343.38
References & Citations
[1]Vela M, et al. Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease. ACS Chem Neurosci. 2022 Jan 19;13 (2) :275-287.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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