IND 1316

IND 1316 is an orally active, blood-brain barrier permeable AMPK activator with neuroprotective effects in animal models of Huntington's disease. IND 1316 can be used for research on neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease[1].

Product Specifications

CAS Number

[1888473-12-8]

UNSPSC

12352005

Target

AMPK

Type

Reference compound

Related Pathways

Epigenetics; PI3K/Akt/mTOR

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ind-1316.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(C2=CC(OCC3=CC=CC=C3)=CC=C2)C4=C(C=CC=C4)N1)O

Molecular Formula

C22H17NO3

Molecular Weight

343.38

References & Citations

[1]Vela M, et al. Neuroprotective Effect of IND1316, an Indole-Based AMPK Activator, in Animal Models of Huntington Disease. ACS Chem Neurosci. 2022 Jan 19;13 (2) :275-287.