DOTA.SA.FAPi (TFA)
DOTA.SA.FAPi TFA inhibits fibroblast activation protein (FAP) with an IC50 of 0.9 nM. DOTA.SA.FAPi TFA targets protease PREP with an IC50 of 5.4 μM. DOTA.SA.FAPi TFA can be used a PET tracer, when labeled with 68Ga, and used for research about cancer[1]. DOTA.SA.FAPi (TFA) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
Product Specifications
UNSPSC
12352209
Target
FAP; Prolyl Endopeptidase (PREP) ; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dota-sa-fapi-tfa.html
Purity
99.26
Solubility
H2O : ≥ 50 mg/mL
Smiles
O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(NCCNC(C2=O)=C(NCCCCOC3=CC(C(C(NCC(N4[C@H](C#N)CC(F)(F)C4)=O)=O)=CC=N5)=C5C=C3)C2=O)=O)CC1.OC(C(F)(F)F)=O
Molecular Formula
C45H56F5N11O14
Molecular Weight
1069.98
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
RDC Peptide
Available Sizes
Frequently Asked Questions
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