ATG14L Rabbit rabbit pAb
Miscellaneous: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
Product Specifications
Background
Miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
UniProt
Q6ZNE5
Swiss Prot
Q6ZNE5
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein of ATG14L
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071) . Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071) . Accumulates on highly curved PtdIns (3) P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity) . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity) . .
Other Product Names
Beclin 1-associated autophagy-related key regulator (Barkor; Autophagy-related protein 14-like protein; Atg14L)
Gene ID (Human)
22863
Available Sizes
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