ATG14L Rabbit rabbit pAb

Miscellaneous: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

Product Specifications

Background

Miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

UniProt

Q6ZNE5

Swiss Prot

Q6ZNE5

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Protein of ATG14L

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF

Concentration

1 mg/ml

Dilution

IHC-p 1:50-300

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071) . Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071) . Accumulates on highly curved PtdIns (3) P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity) . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity) . .