BMS-641988

BMS-641988 (compound 23) is an oral active nonsteroidal androgen receptor antagonist with the Ki of 1.7 nM. BMS-641988 shows anticancer activity[1].

Product Specifications

CAS Number

[1093276-09-5]

UNSPSC

12352005

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bms-641988.html

Purity

99.70

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@]3([H])[C@](C(N(C4=CC(C(F)(F)F)=C(C=C4)C#N)C3=O)=O)([H])[C@@](O1)([C@@H](C2)NS(CC)(=O)=O)C

Molecular Formula

C20H20F3N3O5S

Molecular Weight

471.45

References & Citations

[1]Balog A, et al. Discovery of BMS-641988, a Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer. ACS Med Chem Lett. 2015;6 (8) :908-912. Published 2015 Jun 19.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC211477L4V 200 µL

IL23 Receptor (IL23R) (NM_144701) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

NBP2-34753PE 0.1 mL

Mouse Monoclonal L1CAM Antibody (SPM275) [PE]

Ask

View Details

162088 25 mg

6-Amino-7-fluoro-3,4-dihydro-2 (1H) -Isoquinolinecarboxylic Acid 1,1-Dimethylethyl Ester

Ask

View Details

279415-01 25 mg

N-2- (Hydroxyethyl) -L-valine

Ask

View Details

279415-02 50 mg

N-2- (Hydroxyethyl) -L-valine

Ask

View Details

279415-03 100 mg

N-2- (Hydroxyethyl) -L-valine

Ask

View Details