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Anti-DFNA5 GSDME Antibody

Boster Bio Anti-DFNA5 GSDME Antibody catalog # A32407. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Gasdermin-E

Gene Name

GSDME

UniProt

O60443

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to the 264-309 of Human DFNA5.

Clonality

Polyclonal

Tissue Specificity

Expressed in cochlea. Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53 (PubMed:16897187, PubMed:18223688) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

54555 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Gasdermin-E

Subcellular Location

Gasdermin-E, N-terminal: Cell membrane

Protein Name

Gasdermin-E

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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