Anti-DFNA5 GSDME Antibody
Boster Bio Anti-DFNA5 GSDME Antibody catalog # A32407. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Gasdermin-E
Gene Name
GSDME
UniProt
O60443
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the 264-309 of Human DFNA5.
Clonality
Polyclonal
Tissue Specificity
Expressed in cochlea. Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53 (PubMed:16897187, PubMed:18223688) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
54555 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Gasdermin-E
Subcellular Location
Gasdermin-E, N-terminal: Cell membrane
Protein Name
Gasdermin-E
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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