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Anti-DREG ADGRG6 Antibody

Boster Bio Anti-DREG ADGRG6 Antibody catalog # A32344. Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Adhesion G-protein coupled receptor G6; Developmentally regulated G-protein-coupled receptor

Gene Name

ADGRG6

UniProt

Q86SQ4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR126. AA range:1091-1140

Clonality

Polyclonal

Tissue Specificity

Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.

Applications

WB, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane (By similarity) . Couples to G (i) -proteins as well as G (s) -proteins (PubMed:24227709) . Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:24227709) . Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling (By similarity) . May act as a receptor for PRNP which may promote myelin homeostasis (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

136695 MW

Gene Name Synonym

Adhesion G-protein coupled receptor G6

Subcellular Location

Cell membrane

Protein Name

Adhesion G-protein coupled receptor G6

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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