Anti-LECT1 CNMD Antibody
Boster Bio Anti-LECT1 CNMD Antibody catalog # A32278. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Leukocyte cell-derived chemotaxin 1 ; Chondromodulin
Gene Name
CNMD
UniProt
O75829
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human LECT1 (NP_008946.1) .
Clonality
Polyclonal
Tissue Specificity
Detected in cartilage and cardiac valves (at protein level) . Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level) . Expression is decreased cardiac valves of patients with valvular heart disease (at protein level) . Weakly expressed in chondrosarcoma.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
37102 MW
Gene Name Synonym
Leukocyte cell-derived chemotaxin 1
Subcellular Location
Chondromodulin-1: Secreted, extracellular space, extracellular matrix. Accumulated in the inter- territorial matrix of cartilage.
Protein Name
Leukocyte cell-derived chemotaxin 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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