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Anti-ADCK3 (N323) COQ8A Antibody

Boster Bio Anti-ADCK3 (N323) COQ8A Antibody catalog # A32273. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Atypical kinase COQ8A, mitochondrial ;2.7.-.-

Gene Name

COQ8A

UniProt

Q8NI60

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 293-353 of Human ADCK3.

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294) . Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294) . Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PubMed:25498144, PubMed:27499294) . Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

71950 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Atypical kinase COQ8A, mitochondrial

Subcellular Location

Mitochondrion

Protein Name

Atypical kinase COQ8A, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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