Anti-MESDC2 Antibody
Boster Bio Anti-MESDC2 Antibody catalog # A32230. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
LRP chaperone MESD ; LDLR chaperone MESD; Mesoderm development LRP chaperone MESD
Gene Name
MESD
UniProt
Q14696
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human MESDC2 (NP_055969.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs) . Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell- surface expression of LRP4 (By similarity) . May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
26077 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
LRP chaperone MESD
Subcellular Location
Endoplasmic reticulum
Protein Name
LRP chaperone MESD
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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