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Anti-HASP HASPIN Antibody

Boster Bio Anti-HASP HASPIN Antibody catalog # A31862. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Serine/threonine-protein kinase haspin;2.7.11.1; Germ cell-specific gene 2 protein; H-haspin; Haploid germ cell-specific nuclear protein kinase; HASPIN

Gene Name

HASPIN

UniProt

Q8TF76

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 270-350

Clonality

Polyclonal

Tissue Specificity

Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferating cell lines.

Applications

WB, ELISA

Purification

HASP antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

88495 MW

Gene Name Synonym

Serine/threonine-protein kinase haspin

Subcellular Location

Nucleus

Protein Name

Serine/threonine-protein kinase haspin

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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