Anti-ICT1 Antibody (C-term)
Boster Bio Anti-ICT1 Antibody (C-term) (Catalog # A31846-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
Synonyms
Peptidyl-tRNA hydrolase ICT1, mitochondrial, 39S ribosomal protein L58, mitochondrial, MRP-L58, Digestion substraction 1, DS-1, Immature colon carcinoma transcript 1 protein, ICT1, DS1
Gene Name
MRPL58
UniProt
Q14197
Host
Rabbit
Reactivity
Human
Immunogen
This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.
Clonality
Polyclonal
Tissue Specificity
Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.
Applications
IHC-P, WB
Field of Research
Cancer, Mitochondria
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
2018612033878294338782942018612033878294
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
23630 Da
Subcellular Location
Mitochondrion
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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