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Anti-ICT1 Antibody (C-term)

Boster Bio Anti-ICT1 Antibody (C-term) (Catalog # A31846-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Synonyms

Peptidyl-tRNA hydrolase ICT1, mitochondrial, 39S ribosomal protein L58, mitochondrial, MRP-L58, Digestion substraction 1, DS-1, Immature colon carcinoma transcript 1 protein, ICT1, DS1

Gene Name

MRPL58

UniProt

Q14197

Host

Rabbit

Reactivity

Human

Immunogen

This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.

Clonality

Polyclonal

Tissue Specificity

Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.

Applications

IHC-P, WB

Field of Research

Cancer, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

2018612033878294338782942018612033878294

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

23630 Da

Subcellular Location

Mitochondrion

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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