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Anti-ICT1 MRPL58 Antibody

Boster Bio Anti-ICT1 MRPL58 Antibody catalog # A31846. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Peptidyl-tRNA hydrolase ICT1, mitochondrial;3.1.1.29;39S ribosomal protein L58, mitochondrial

Gene Name

MRPL58

UniProt

Q14197

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human ICT1 (NP_001536.1) .

Clonality

Polyclonal

Tissue Specificity

Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

23630 MW

Gene Name Synonym

Peptidyl-tRNA hydrolase ICT1, mitochondrial

Subcellular Location

Mitochondrion

Protein Name

Peptidyl-tRNA hydrolase ICT1, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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