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Anti-Histone H2A.z/H2AZ1 Antibody

Boster Bio Anti-Histone H2A.z/H2AZ1 Antibody catalog # A31256. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Synonyms

H2AFZ; Histone H2A; H2AZ1; H2AZ; H2A/z

Gene Name

H2AZ1

UniProt

P0C0S5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human Histone H2A.z/H2AZ1 recombinant protein (Position: G3-K126) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Gene Name Synonym

H2A.Z variant histone 1

Protein Name

Histone H2A.Z

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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