Anti-NEURL/NEURL1 Antibody
Boster Bio Anti-NEURL/NEURL1 Antibody catalog # A30740-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
NEURL (Neuralized-like protein 1A) is also named as NEURL1, NEURL1A, RNF67.Neurl1 is a RING-dependent E3 ubiquitin ligase that can regulate Notch signaling in mammals and it expression promotes lysosomal degradation of Jagged1 in cells and blocks signaling from Jagged1-expressing cells to neighboring Notch-expressing cells. Neurl-dependent turnover of Jagged1 and inhibition of Notch signaling depends upon N-terminal myristoylation and plasma membrane localization of Neurl1 (PMID:18077452) .This antibody is specific to NEURL.
Synonyms
Neu; h-neuralized 1; h neuralized 1; h neu; EC:2.3.2.27
Gene Name
NEURL1
UniProt
O76050
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human NEURL/NEURL1 recombinant protein (Position: N3-T343) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Neuralized E3 ubiquitin protein ligase 1
Protein Name
E3 ubiquitin-protein ligase NEURL1
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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