Anti-KRT28 Antibody (C-term)
Boster Bio Anti-KRT28 Antibody (C-term) (Catalog # A15408) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.
Synonyms
HGNC:30842
Gene Name
KRT28
UniProt
Q7Z3Y7
Host
Rabbit
Reactivity
Human
Immunogen
This KRT28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-460 amino acids from the C-terminal region of human KRT28.
Clonality
Polyclonal
Tissue Specificity
Strongly expressed in skin and scalp, and weak expression observed in thymus. In the hair follicle, expressed in Henle layer, Huxley layer and in the irs cuticle. Expression extends from the bulb region up to the point of differentiation into the three layers Also present in the medulla of beard hair (at protein level)
Applications
WB
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs) .
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
50567 Da
Applications Notes
WB: 1:1000
Subcellular Location
Cytoplasm {ECO:0000250|UniProtKB:A6BLY7}.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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