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Anti-UBP51 USP51 Antibody

Boster Bio Anti-UBP51 USP51 Antibody catalog # A13844. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ubiquitin carboxyl-terminal hydrolase 51

Gene Name

USP51

UniProt

Q70EK9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Tissue Specificity

Expressed in prostate, brain, lung, aorta and kidney.

Applications

WB, ELISA

Purification

UBP51 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16' (H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998) . USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

79756 MW

Gene Name Synonym

Ubiquitin carboxyl-terminal hydrolase 51

Subcellular Location

Chromosome

Protein Name

Ubiquitin carboxyl-terminal hydrolase 51

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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