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Anti-ASAH3 Antibody

Boster Bio Anti-ASAH3 Antibody catalog # A12775. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Alkaline ceramidase 1; AlkCDase 1; Alkaline CDase 1;3.5.1.23; Acylsphingosine deacylase 3; N-acylsphingosine amidohydrolase 3; ACER1; ASAH3

Gene Name

ACER1

UniProt

Q8TDN7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from ASAH3 . at AA range: 100-180

Tissue Specificity

Mainly expressed in epidermis. .

Applications

WB, ELISA

Purification

Immunogen affinity purified

Sensitivity

<10pg/ml

Concentration

1 mg/mL

Form

Liquid

Function

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo- phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

31095 MW

Gene Name Synonym

Alkaline ceramidase 1

Subcellular Location

Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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