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Anti-DPH2 Antibody

Boster Bio Anti-DPH2 Antibody catalog # A12485-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) . When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Mutants of the DPH1, DPH2, and DPH5 (611075) genes, involved in diphthamide biosynthesis, were identified as resistant to both anthrax toxin and diphtheria toxin. This antibody works well in WB, IP, IHC and IF application.

Synonyms

S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2; HsDph2; DPH2L2; Diphtheria toxin resistance protein 2; 2- (3-amino-3-carboxypropyl) histidine synthase subunit 2

Gene Name

DPH2

UniProt

Q9BQC3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

E.coli-derived human DPH2 recombinant protein (Position: E192-G487) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Gene Name Synonym

Diphthamide biosynthesis 2

Protein Name

2- (3-amino-3-carboxypropyl) histidine synthase subunit 2

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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