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Anti-POMGNT2 Antibody

Boster Bio Anti-POMGNT2 Antibody catalog # A11987. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

Gene Name

POMGNT2

UniProt

Q8NAT1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human POMGNT2 (NP_116195.2) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

O-linked mannose beta-1,4-N- acetylglucosaminyltransferase that transfers UDP-N-acetyl-D- glucosamine to the 4-position of the mannose to generate N-acetyl- D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4- (phosphate- 6-) mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

66615 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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