Emodin-1-O-β-D-glucopyranoside

Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM[1].

Product Specifications

CAS Number

[38840-23-2]

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/emodin-1-o-beta-d-glucopyranoside.html

Purity

99.79

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C1C2=C(C=C(O)C=C2O)C(C3=CC(C)=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=C13)=O

Molecular Formula

C21H20O10

Molecular Weight

432.38

References & Citations

[1]Uddin Z, et al. Potent bacterial neuraminidase inhibitors, anthraquinone glucosides from Polygonumcuspidatum and their inhibitory mechanism. J Ethnopharmacol. 2016 Dec 4;193:283-292.