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Anti-TFDP3 Antibody (N-term)

Boster Bio Anti-TFDP3 Antibody (N-term) (Catalog # A11396) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.

Synonyms

Transcription factor Dp family member 3, Cancer/testis antigen 30, CT30, Hepatocellular carcinoma-associated antigen 661, TFDP3, DP4, HCA661

Gene Name

TFDP3

UniProt

Q5H9I0

Host

Rabbit

Reactivity

Human

Immunogen

This TFDP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the N-terminal region of human TFDP3.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.

Applications

WB

Field of Research

Cell Biology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G (1) to S phase.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

44967 Da

Applications Notes

WB: 1:1000

Subcellular Location

Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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