Anti-TECPR1 Antibody (C-term)
Boster Bio Anti-TECPR1 Antibody (C-term) (Catalog # A11073) . Tested in IHC-P, Flow Cytometry, WB application (s) . This antibody reacts with Human.
Product Specifications
Synonyms
Tectonin beta-propeller repeat-containing protein 1, TECPR1, KIAA1358
Gene Name
TECPR1
UniProt
Q7Z6L1
Host
Rabbit
Reactivity
Human
Immunogen
This TECPR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1094-1122 amino acids from the C-terminal region of human TECPR1.
Clonality
Polyclonal
Applications
IHC-P, Flow Cytometry, WB
Field of Research
Cell Biology, Autophagy, Lysosome
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns (3) P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
129696 Da
Subcellular Location
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns (3) P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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