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Anti-PLD6 Antibody (Center)

Boster Bio Anti-PLD6 Antibody (Center) (Catalog # A10904) . Tested in WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Mitochondrial cardiolipin hydrolase, 31--, Choline phosphatase 6, Mitochondrial phospholipase, MitoPLD, Phosphatidylcholine-hydrolyzing phospholipase D6, Phospholipase D6, PLD 6, Protein zucchini homolog, PLD6

Gene Name

PLD6

UniProt

Q8N2A8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PLD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from of human PLD6.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in testis and ovary, but not limited to gonads (at protein level) (PubMed:17028579, PubMed:21397847) . It is also found in brain, heart, pituitary gland, prostate, pancreas, thyroid, bone marrow, lung and muscle (PubMed:21397847) .

Applications

WB

Field of Research

Metabolism, Signal Transduction, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

17028579213978472806349626711011170285792459996226678338170285792671101124599962266783382139784826678338213978472139784821397847

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

28273 Da

Applications Notes

WB: 1:2000

Subcellular Location

Mitochondrion outer membrane; Single-pass membrane protein. Golgi apparatus {ECO:0000250|UniProtKB:Q5SWZ9}. Note=Localization in the mitochondrial outer membrane is found in different cell types where phospholipase is the predominant activity, however, in pachytene spermatocytes and spermatids of mouse testes where nuclease activity is predominant, localization is restricted to the Golgi, suggesting this enzyme is localized in different subcellular compartments depending on the role (phospholipase or nuclease) it needs to play in each cell type and developmental stage.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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