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Anti-Wee1-like protein kinase 2 WEE2 Antibody

Boster Bio Anti-Wee1-like protein kinase 2 WEE2 Antibody (Catalog# A10843) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

WEE2; WEE1B; Wee1-like protein kinase 2; Wee1-like protein kinase 1B; Wee1B kinase

Gene Name

WEE2

UniProt

P0C1S8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human WEE2. Immunogen sequence location: 151 - 200

Clonality

Polyclonal

Tissue Specificity

Expressed in testis.

Applications

WB, ELISA

Field of Research

Cell Biology, Cell Cycle, Developmental Biology, Germ Cell Markers, Kinases/Phosphatases, Protein Phosphorylation, Reproduction, Ser/Thr Kinases, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity) .

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

62925 MW

Gene Name Synonym

Wee1-like protein kinase 2

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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