Anti-TUBB6 Antibody (Center)
Boster Bio Anti-TUBB6 Antibody (Center) (Catalog # A10831) . Tested in WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity) .
Synonyms
Tubulin beta-6 chain, Tubulin beta class V, TUBB6
Gene Name
TUBB6
UniProt
Q9BUF5
Host
Rabbit
Reactivity
Human
Immunogen
This TUBB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-166 amino acids from the Central region of human TUBB6.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues.
Applications
WB
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
49857 Da
Applications Notes
WB: 1:2000
Subcellular Location
Cytoplasm, cytoskeleton.
Prediction Reactivity
Bovine, Monkey, Mouse
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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