Anti-ATP6V1A Antibody
Boster Bio Anti-ATP6V1A Antibody catalog # A10401. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
V-type proton ATPase catalytic subunit A; V-ATPase subunit A;7.1.2.2; V-ATPase 69 kDa subunit; Vacuolar ATPase isoform VA68; Vacuolar proton pump subunit alpha; ATP6V1A; ATP6A1, ATP6V1A1, VPP2
Gene Name
ATP6V1A
UniProt
P38606
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human ATP6V1A
Clonality
Polyclonal
Tissue Specificity
High expression in the skin.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe (2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633) . May play a role in neurite development and synaptic connectivity (PubMed:29668857) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
68304 MW
Gene Name Synonym
V-type proton ATPase catalytic subunit A
Subcellular Location
Cytoplasm
Protein Name
V-type proton ATPase catalytic subunit A
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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